王宏宇实验室

Ouyang Q, Chen QL, Ke SY, Ding LF, Yang XY, Rong P, Feng WK, Cao Y, Wang Q, Li M, Su S, Wei W, Liu MJ, Liu J, Zhang X, Li JZ, Wang HY* and Chen S* (2023) Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle. Dev Cell 58, 289-305

Quan C, Zhu SS, Wang RZ, Chen JM, Chen QL, Li M, Su S, Du Q, Liu MJ, Wang HY* and Chen S* (2022) Impaired SERCA2a phosphorylation causes diabetic cardiomyopathy through impinging on cardiac contractility and precursor protein processing. Life Metabolism DOI: 10.1093/lifemeta/loac013 (* corresponding authors)

Zhu SS, Quan C, Wang RZ, Liang DR, Su S, Rong P, Zhou K, Yang XY, Chen QL, Li M, Du Q, Zhang JZ, Fang L, Wang HY* and Chen S* (2022) The RalGAPα1−RalA signal module protects cardiac function through regulating calcium homeostasis. Nat Commun 13: 4278 DOI: 10.1038/s41467-022-31992-z (* corresponding authors)

Wei W, Chen QL, Liu MJ, Sheng Y, OuYang Q, Feng WK, Yang XY, Ding LF, Su S, Zhang JZ, Fang L, Vidal-Puig A, Wang HY* and Chen S* (2022) TRIM24 is an insulin-responsive regulator of P-bodies. Nat Commun 13: 3972 DOI: 10.1038/s41467-022-31735-0 (* corresponding authors)

Chen ZY, Sun YT, Wang ZM, Hong J, Xu M, Zhang FT, Zhou XQ, Rong P, Wang Q, Wang HY, Wang H*, Chen S* and Chen L* (2022) Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARg. Plos Biol 20(1): e3001522 DOI: 10.1371/journal.pbio.3001522 (* corresponding authors)

Yang XY, Chen QL, OuYang Q, Rong P, Feng WK, Quan C, Li M, Jiang Q, Liang H, Zhao TJ, Wang HY* and Chen S*. (2021) Tissue-specific splicing and dietary interaction of a mutant As160 allele determine muscle metabolic fitness in rodents. Diabetes doi: 10.2337/db21-0039(* corresponding author)

Quan C, Du Q, Li M, Wang RZ, Su S, Zhu SS, Chen QL, Sheng Y, Chen L, Wang H, Campbell DG, MacKintosh C, Yang ZZ, Ouyang KF, Wang HY* and Chen S* (2020) A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis. Nat Commun 11(1): 2186 doi: 10.1038/s41467-020-16116-9 (* corresponding author)

Chen QL, Rong P, Zhu SS, Yang XY, Ouyang Q, Wang HY and Chen S* (2019) Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control. Science Advances 5(4): eaav4116 (* corresponding author)

Quan C, Li M, Du Q, Chen QL, Wang H, Campbell D, Fang L, Xue B, MacKintosh C, Gao X, Ouyang KF, Wang HY and Chen S* (2019) SPEG controls calcium re-uptake into the sarcoplasmic reticulum through regulating SERCA2a by its second kinase-domain. Circ Res 124(5): 712-726 (* corresponding author)

Sheng Y, Li HL, Liu MJ, Xie BX, Wei W, Wu JW, Meng FG*, Wang HY* and Chen S* (2019) A Manganese-Superoxide Dismutase From Thermus thermophilus HB27 Suppresses Inflammatory Responses and Alleviates Experimentally Induced Colitis. Inflamm Bowel Dis pii: izz097. doi: 10.1093/ibd/izz097 (* corresponding author)